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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1351322Generated: October 26, 2026

(2-(4-Fluorophenyl)ethyl)(methyl)amine → 4-Bromo-thiophene-2-carboxylic acid [2-(4-fluorophenyl)-ethyl]-methyl-amide

https://huagongshe.com/reaction/1351322

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2-(4-Fluorophenyl)ethyl)(methyl)amineHCID 120234—
Reactant4-Bromo-2-thiophenecarboxylic AcidHCID 610409—
Product4-Bromo-thiophene-2-carboxylic acid [2-(4-fluorophenyl)-ethyl]-methyl-amideHCID 86601000—

Reaction Steps

From 4-bromo-thiophene-2-carboxylic acid and 1.47 g of [2-(4-fluorophenyl)-ethyl]-methyl-amine (the compound of Preparation Example 14) (1.98 g), a colorless solid (2.53 g) was obtained, in the same way as Preparation Example 118-b).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07217723B2
Source datasetuspto-grants-2007_05
ORD IDord-0d4dc13ef44647b5ae866a555b0c4531
Source noteuspto-grants-2007_05