HuagongsheHuagongshe Chemistry Print Report · For research reference only
(+-)-alpha-Methyl-alpha-phenylsuccinimide → 3-Methyl-3-phenylpyrrolidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (+-)-alpha-Methyl-alpha-phenylsuccinimide | HCID 92154 | — |
| Reactant | Aluminium lithium hydride | HCID 21226445 | — |
| Product | 3-Methyl-3-phenylpyrrolidine | HCID 21098616 | — |
Reaction Steps
3-Methyl-3-phenyl-pyrrolidine, which was synthesized by reducing 3-methyl-3-phenyl pyrrolidine-2,5-dione with aluminum lithium hydride, was used as the amine to carry out the reaction according to <method α>. A purification by silica gel column chromatography (hexane/ethyl acetate) was carried out, and, the title compound (7 mg) was obtained as a colorless solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07217723B2 |
| Source dataset | uspto-grants-2007_05 |
| ORD ID | ord-66286f62f78e4d4ebbd21eb86cd45d7a |
| Source note | uspto-grants-2007_05 |