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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1351334Generated: November 1, 2026

(+-)-alpha-Methyl-alpha-phenylsuccinimide → 3-Methyl-3-phenylpyrrolidine

https://huagongshe.com/reaction/1351334

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(+-)-alpha-Methyl-alpha-phenylsuccinimideHCID 92154—
ReactantAluminium lithium hydrideHCID 21226445—
Product3-Methyl-3-phenylpyrrolidineHCID 21098616—

Reaction Steps

3-Methyl-3-phenyl-pyrrolidine, which was synthesized by reducing 3-methyl-3-phenyl pyrrolidine-2,5-dione with aluminum lithium hydride, was used as the amine to carry out the reaction according to <method α>. A purification by silica gel column chromatography (hexane/ethyl acetate) was carried out, and, the title compound (7 mg) was obtained as a colorless solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07217723B2
Source datasetuspto-grants-2007_05
ORD IDord-66286f62f78e4d4ebbd21eb86cd45d7a
Source noteuspto-grants-2007_05