HuagongsheHuagongshe Chemistry Print Report · For research reference only
Formamide → 6-methylquinazolin-4-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Formamide | HCID 713 | — |
| Reactant | 2-Amino-5-methylbenzoic acid | HCID 76255 | — |
| Solvent | Water | HCID 962 | — |
| Product | 6-methylquinazolin-4-ol | HCID 135452442 | — |
Reaction Steps
8 g of 5-methyl 2-aminobenzoic acid and 15 ml formamide was heated at −170° C. 1.5 hour. Water was added and the solid filtered to give 7.3 g of 6-methyl 4-quinazolinone as a light brown-white solid, mp—268° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07217737B2 |
| Source dataset | uspto-grants-2007_05 |
| ORD ID | ord-e441a7bc50174f1db99b2c2344b810db |
| Source note | uspto-grants-2007_05 |