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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1351556Generated: November 3, 2026

7H-Purine, 6-chloro-7-methyl- → (7-Methyl-7H-purin-6-yl)-[1-(2-phenyl-ethanesulfonyl)-piperidin-4-ylmethyl]-amine

https://huagongshe.com/reaction/1351556

Reaction equation

Participants

RoleNameHCIDCharge
Reactant7H-Purine, 6-chloro-7-methyl-HCID 95057—
Reactant[1-(2-Phenylethylsulfonyl)piperidin-4-yl]methanamineHCID 22135729—
Product(7-Methyl-7H-purin-6-yl)-[1-(2-phenyl-ethanesulfonyl)-piperidin-4-ylmethyl]-amineHCID 23577259—

Reaction Steps

EXAMPLE 85 was prepared from C-[1-(2-phenyl-ethanesulfonyl)-piperidin-4-yl]-methylamine and 6-chloro-7-methyl-7H-purine (6-chloro-7-methyl-7H-purine was prepared according to G. B. Eilon, J. Org. Chem., 27:2478–2491(1962): MS (m+1)=415.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07217716B2
Source datasetuspto-grants-2007_05
ORD IDord-2176bf4f45d64aa88153fdd48c30ad86
Source noteuspto-grants-2007_05