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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1351653Generated: November 1, 2026

o-Fluorobenzaldehyde → 1-fluoro-2-{(E)-2-[4-(phenylsulfonyl)phenyl]vinyl}benzene

https://huagongshe.com/reaction/1351653

Reaction equation

Participants

RoleNameHCIDCharge
Reactanto-FluorobenzaldehydeHCID 67970—
ReactantDimethyl[4-(phenylsulfonyl)benzyl]phosphonateHCID 15247537—
Product1-fluoro-2-{(E)-2-[4-(phenylsulfonyl)phenyl]vinyl}benzeneHCID 21099401—

Reaction Steps

The title compound was prepared from dimethyl [4-(phenylsulfonyl)benzyl]phosphonate (Step 2) and 2-fluorobenzaldehyde according to the method of Example 46 Step 5. δH (500 MHz, CDCl3): 7.97–7.92 (4H, m), 7.63–7.55 (4H, m), 7.52–7.49 (2H, m), 7.35 (1H, d, J=16.5 Hz), 7.30–7.25 (1H, m), 7.18–7.14 (2H, m), 7.10–7.06 (1H, m).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07217740B2
Source datasetuspto-grants-2007_05
ORD IDord-f38096f10a4c4d018472a7889200f7cd
Source noteuspto-grants-2007_05