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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 135177Generated: October 27, 2026

Methanol → 8-Benzyl-2-[1-[3,5-bis(trifluoromethyl)phenyl]-2-hydroxyethoxy]-1-phenyl-8-azabicyclo[3.2.1]octane-6-carbonitrile

https://huagongshe.com/reaction/135177

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethanolHCID 887—
ReactantSodium ionHCID 923—
ReactantBorohydrideHCID 28123—
ReactantMethyl 2-[(8-benzyl-6-cyano-1-phenyl-8-azabicyclo[3.2.1]octan-2-yl)oxy]-2-[3,5-bis(trifluoromethyl)phenyl]acetateHCID 88039289—
Product8-Benzyl-2-[1-[3,5-bis(trifluoromethyl)phenyl]-2-hydroxyethoxy]-1-phenyl-8-azabicyclo[3.2.1]octane-6-carbonitrileHCID 88039642—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-3fe0ac52475c429b8190e946ed5425dc
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)