Sodium Hydroxide → HCID 86585781, compound

Participants

Reaction Steps

To a solution of [8-(N-benzyl-tert-butoxycarbonylamino)-6,7,8,9-tetrahydro-5H-benzocyclohepten-2-yloxy]acetic acid ethyl ester (2.5 g) in ethanol (25 ml) was added 1N sodium hydroxide aqueous solution at 5° C., and the solution was stirred at room temperature for 1 hour. The resulting solution was evaporated in vacuo to afford sodium [8-(N-benzyl-tert-butoxycarbonylamino)-6,7,8,9-tetrahydro-5H-benzocyclohepten-2-yloxy]acetate (2.35 g).

Provenance & Evidence