Hydrochloric Acid → HCID 69329379, compound

Participants

Reaction Steps

To N-(3-isopropoxy-6,7,8,9-tetrahydro-5H-benzocyclo-hepten-6-yl)-N-[(2S)-3-phenoxy-2-(triethylsilyloxy)propyl]-tert-butoxycarbonylamine (79 mg) was added 4N hydrogen chloride in ethyl acetate (3 ml) at room temperature, and the mixture was stirred at room temperature for 1 hour. After evaporation in vacuo, the residue was triturated with diisopropyl ether and dried in vacuo to give (2S)-1-(3-isopropoxy-6,7,8,9-tetrahydro-5H-benzocyclohepten-6-yl)amino-3-phenoxy-2-propanol hydrochloride (35 mg). (+) APCI-MASS (m/z): 370 (M-HCl+H)+

Provenance & Evidence