4-Aminopyridine → 1-(2,6-Dichlorophenyl)-3-(4-pyridyl)urea

HRID 1352115노트

반응식

HRID 1352115 반응식
[NH2:1][C:2]1[CH:7]=[CH:6][N:5]=[CH:4][CH:3]=1.[Cl:8][C:9]1[CH:14]=[CH:13][CH:12]=[C:11]([Cl:15])[C:10]=1[N:16]=[C:17]=[O:18]>C1(C)C=CC=CC=1>[Cl:8][C:9]1[CH:14]=[CH:13][CH:12]=[C:11]([Cl:15])[C:10]=1[NH:16][C:17]([NH:1][C:2]1[CH:7]=[CH:6][N:5]=[CH:4][CH:3]=1)=[O:18]

참가 물질

4

반응물 2

HCID 17274-AminopyridineHCID 6045371,3-Dichloro-2-isocyanatobenzene

생성물 1

HCID 46105601-(2,6-Dichlorophenyl)-3-(4-pyridyl)urea

시약·촉매·용매 1

HCID 1140Toluene용매

반응 조건

온도
110 °C

실험 절차

4-Aminopyridine (100 mg, 1.06 mmol) and 2,6-dichlorophenyl isocyanate (219.7 mg, 1.17 mmol) were dissolved in toluene, and the mixture was then stirred at 110° C. for 4 hr.

출처 및 근거

ORD 기록
ord-529c01dba7494736a5222002e7373eff
출처 데이터셋
uspto-grants-2007_05
특허 번호
US07217722B2

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