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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1352115Generated: October 25, 2026

4-Aminopyridine → 1-(2,6-Dichlorophenyl)-3-(4-pyridyl)urea

https://huagongshe.com/reaction/1352115

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-AminopyridineHCID 1727—
Reactant1,3-Dichloro-2-isocyanatobenzeneHCID 604537—
SolventTolueneHCID 1140—
Product1-(2,6-Dichlorophenyl)-3-(4-pyridyl)ureaHCID 4610560—

Reaction Conditions

Temperature110 °C

Reaction Steps

4-Aminopyridine (100 mg, 1.06 mmol) and 2,6-dichlorophenyl isocyanate (219.7 mg, 1.17 mmol) were dissolved in toluene, and the mixture was then stirred at 110° C. for 4 hr.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07217722B2
Source datasetuspto-grants-2007_05
ORD IDord-529c01dba7494736a5222002e7373eff
Source noteuspto-grants-2007_05