4-Aminopyridine → HCID 17838287, compound

HRID 1352118Notes

Reaction equation

HRID 1352118 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][N:5]=[CH:4][CH:3]=1.[Cl:8][C:9]1[CH:14]=[C:13]([Cl:15])[CH:12]=[CH:11][C:10]=1[N:16]=[C:17]=[O:18]>C1(C)C=CC=CC=1>[Cl:8][C:9]1[CH:14]=[C:13]([Cl:15])[CH:12]=[CH:11][C:10]=1[NH:16][C:17]([NH:1][C:2]1[CH:7]=[CH:6][N:5]=[CH:4][CH:3]=1)=[O:18]

Participants

4

Reactant 2

HCID 17274-AminopyridineHCID 757892,4-Dichlorophenyl isocyanate

Product 1

HCID 17838287HCID 17838287, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Conditions

Temperature
110 °C

Procedure

4-Aminopyridine (100 mg, 1.06 mmol) and 2,4-dichlorophenyl isocyanate (219.7 mg, 1.17 mmol, 1.1 eq) were dissolved in toluene, and the mixture was then stirred at 110° C. for 4 hr.

Sources & evidence

ORD record
ord-2dd8a63fed4245a9b5cefffe5ef27b4d
Source dataset
uspto-grants-2007_05
Patent number
US07217722B2

Reaction notes

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