4-Aminopyridine → HCID 4580695, compound

HRID 1352120Notes

Reaction equation

HRID 1352120 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][N:5]=[CH:4][CH:3]=1.[CH:8]1([N:14]=[C:15]=[O:16])[CH2:13][CH2:12][CH2:11][CH2:10][CH2:9]1>C1(C)C=CC=CC=1>[CH:8]1([NH:14][C:15]([NH:1][C:2]2[CH:7]=[CH:6][N:5]=[CH:4][CH:3]=2)=[O:16])[CH2:13][CH2:12][CH2:11][CH2:10][CH2:9]1

Participants

4

Reactant 2

HCID 17274-AminopyridineHCID 18502Cyclohexyl isocyanate

Product 1

HCID 4580695HCID 4580695, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Conditions

Temperature
110 °C

Procedure

4-Aminopyridine (100 mg, 1.06 mmol) and cyclohexyl isocyanate (146.3 mg, 1.17 mmol) were dissolved in toluene, and the mixture was then stirred at 110° C. for 4 hr.

Sources & evidence

ORD record
ord-f7d673ac36fc4242a58f284113e30ce0
Source dataset
uspto-grants-2007_05
Patent number
US07217722B2

Reaction notes

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