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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1352125Generated: November 2, 2026

HCID 21098484, compound → HCID 21098454, compound

https://huagongshe.com/reaction/1352125

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 21098484HCID 21098484—
CatalystPalladiumHCID 23938—
SolventEthanolHCID 702—
ProductHCID 21098454HCID 2109845482%

Reaction Steps

N-{1-[4-(Benzyloxy)benzyl]-4-piperidyl}-N-(1H-5-indazolyl)amine (Example 142, 33 mg) and palladium-charcoal (10 mg) were suspended in ethanol (3 ml), and the suspension was stirred under a hydrogen atmosphere of 1 atm at room temperature for 18 hr. The reaction mixture was filtered through Celite, and the filtrate was then concentrated to give the title compound (21 mg, yield 82%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07217722B2
Source datasetuspto-grants-2007_05
ORD IDord-a9e3a9161b23437bb8a424970e87c7ed
Source noteuspto-grants-2007_05