HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 21098484, compound → HCID 21098454, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 21098484 | HCID 21098484 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 21098454 | HCID 21098454 | 82% |
Reaction Steps
N-{1-[4-(Benzyloxy)benzyl]-4-piperidyl}-N-(1H-5-indazolyl)amine (Example 142, 33 mg) and palladium-charcoal (10 mg) were suspended in ethanol (3 ml), and the suspension was stirred under a hydrogen atmosphere of 1 atm at room temperature for 18 hr. The reaction mixture was filtered through Celite, and the filtrate was then concentrated to give the title compound (21 mg, yield 82%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07217722B2 |
| Source dataset | uspto-grants-2007_05 |
| ORD ID | ord-a9e3a9161b23437bb8a424970e87c7ed |
| Source note | uspto-grants-2007_05 |