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HRID1352288

反应详情

EQUATION

反应方程式

HRID 1352288 的结构方程式

REACTANTS

反应物

2
结构：Cl.Cl.Clc1ccc(-c2csc(N3CCNCC3)n2)c(Cl)c1
HCID21100173

未命名化合物

结构：CC(C)Oc1ccc(S(C)(=O)=O)cc1C(=O)O
HCID21100237

2-(1-Methylethoxy)-5-(methylsulfonyl)benzoic acid

C11H14O5S

PRODUCTS

生成物

1
结构：CC(C)Oc1ccc(S(C)(=O)=O)cc1C(=O)N1CCN(c2nc(-c3ccc(Cl)cc3Cl)cs2)CC1
HCID21100260

未命名化合物

收率 17%

PROCEDURE

实验过程

Prepared in analogy to example 1 (b) from 2-isopropoxy-5-methanesulfonyl-benzoic acid (Example A1) and 1-[4-(2,4-dichloro-phenyl)-thiazol-2-yl]-piperazine dihydrochloride. The crude material was purified by chromatography (SiO2, methanol/dichloromethane) (yield 17%). MS (m/e): 558.1 ({37Cl}M+H+, 19%), 555.9 ({37Cl35Cl}M+H+, 58%), 554.1 ({35Cl}M+H+, 100%).

WORKUP

后处理

  1. customThe crude material was purified by chromatography (SiO2, methanol/dichloromethane) (yield 17%)