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HRID1352317

反应详情

EQUATION

反应方程式

HRID 1352317 的结构方程式

REACTANTS

反应物

2
结构：CCS(=O)(=O)c1cnc(N2CCNCC2)s1.Cl
HCID21100185

未命名化合物

结构：CC(C)(C)COc1ccc(S(C)(=O)=O)cc1C(=O)O
HCID21100203

未命名化合物

PRODUCTS

生成物

1
结构：CCS(=O)(=O)c1cnc(N2CCN(C(=O)c3cc(S(C)(=O)=O)ccc3OCC(C)(C)C)CC2)s1
HCID21100204

未命名化合物

收率 63%

PROCEDURE

实验过程

Prepared in analogy to example 1 (b) from 2-(2,2-dimethyl-propoxy)-5-methanesulfonyl-benzoic acid (Example A11) and 1-(5-ethanesulfonyl-thiazol-2-yl)-piperazine hydrochloride. The crude material was purified by chromatography (SiO2, ethyl acetate/heptane) followed by trituration in ether to yield the title compound as a white crystalline solid (yield 63%). MS (m/e): 530.2 (M+H+, 64%), 547.2 (M+NH4+, 100%).

WORKUP

后处理

  1. customThe crude material was purified by chromatography (SiO2, ethyl acetate/heptane)