HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(4,5-Dimethyl-1,3-thiazol-2-yl)piperazine → HCID 21100261, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(4,5-Dimethyl-1,3-thiazol-2-yl)piperazine | HCID 19915765 | — |
| Reactant | 2-Isopropoxy-5-methylsulfonylbenzoic acid | HCID 21100237 | — |
| Product | HCID 21100261 | HCID 21100261 | 65% |
Reaction Steps
Prepared in analogy to example 1 (b) from 2-isopropoxy-5-methanesulfonyl-benzoic acid (Example A1) and 1-(4,5-dimethyl-thiazol-2-yl)-piperazine. The crude material was purified by chromatography (SiO2, ethyl acetate/heptane) followed by trituration in ether to yield the title compound as an off-white crystalline solid (yield 65%). MS (m/e): 584.3 (M+H+, 100%), 601.4 (M+NH4+, 60%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07220744B2 |
| Source dataset | uspto-grants-2007_05 |
| ORD ID | ord-7db20309a9a640b083c91f564ee669ef |
| Source note | uspto-grants-2007_05 |