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HRID1352337

反应详情

EQUATION

反应方程式

HRID 1352337 的结构方程式

REACTANTS

反应物

2
结构：Cl.O=S(=O)(c1cccnc1)c1cnc(N2CCNCC2)s1
HCID21100195

未命名化合物

结构：CC(C)Oc1ccc(S(C)(=O)=O)cc1C(=O)O
HCID21100237

2-(1-Methylethoxy)-5-(methylsulfonyl)benzoic acid

C11H14O5S

PRODUCTS

生成物

1
结构：CC(C)Oc1ccc(S(C)(=O)=O)cc1C(=O)N1CCN(c2ncc(S(=O)(=O)c3cccnc3)s2)CC1
HCID21100249

未命名化合物

收率 87%

PROCEDURE

实验过程

Prepared in analogy to example 1 (b) from 2-isopropoxy-5-methanesulfonyl-benzoic acid (Example A1) and 1-[5-(pyridine-3-sulfonyl)-thiazol-2-yl]-piperazine hydrochloride. The crude material was purified by chromatography (SiO2, ethyl acetate/heptane) followed by trituration in ether to yield the title compound as an off-white crystalline solid (yield 87%). MS (m/e): 551.3 (M+H+, 100%).

WORKUP

后处理

  1. customThe crude material was purified by chromatography (SiO2, ethyl acetate/heptane)