反应详情

0.83 mmol 4-(5-trifluoromethyl-[1,3,4]thiadiazol-2-yl)-piperazine-1-carboxylic acid tert-butyl ester in 10 ml of dichloromethane was treated with 6.6 mmol trifluoroacetic acid and stirred for 2 hours at room temperature. The reaction mixture is concentrated to give the title compound as yellowish gum. MS (m/e): 239.1 (M+H+, 100%).

1. concentrationThe reaction mixture is concentrated