HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(5-Trifluoromethyl-[1,3,4]thiadiazol-2-yl)-piperazine trifluoroacetate → HCID 11612866, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(5-Trifluoromethyl-[1,3,4]thiadiazol-2-yl)-piperazine trifluoroacetate | HCID 21100199 | — |
| Reactant | 2-Cyclopropylmethoxy-5-methanesulfonyl-benzoic acid | HCID 21100228 | — |
| Product | HCID 11612866 | HCID 11612866 | — |
Reaction Steps
Prepared in analogy to example 1 (b) from 2-cyclopropylmethoxy-5-methanesulfonyl-benzoic acid (Example A5) and 1-(5-trifluoromethyl-[1,3,4]thiadiazol-2-yl)-piperazine trifluoroacetate (Example 62(b)). The crude material was purified by chromatography (SiO2, dichloromethane/methanol 98:2) to yield the title compound as a colorless solid. MS (m/e): 491.2 (M+H+, 100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07220744B2 |
| Source dataset | uspto-grants-2007_05 |
| ORD ID | ord-f9bdaecf22fe442c94452edca6ce5956 |
| Source note | uspto-grants-2007_05 |