huagongshe.com
HRID1352400

反应详情

EQUATION

反应方程式

HRID 1352400 的结构方程式

REACTANTS

反应物

2
结构：Cl.FC(F)(F)c1cnc(N2CCNCC2)s1
HCID21100200

未命名化合物

结构：CCSc1ccc(S(C)(=O)=O)cc1C(=O)O
HCID21100231

未命名化合物

PRODUCTS

生成物

1
结构：CCSc1ccc(S(C)(=O)=O)cc1C(=O)N1CCN(c2ncc(C(F)(F)F)s2)CC1
HCID21100232

未命名化合物

收率 41%

PROCEDURE

实验过程

Prepared in analogy to example 1 (b) from 2-ethylsulfanyl-5-methanesulfonyl-benzoic acid (Example A23) and 1-(5-trifluoromethyl-thiazol-2-yl)-piperazine hydrochloride (Example 58(c)). The crude material was purified by chromatography (SiO2, ethyl acetate/heptane) to yield the title compound as a white foam (yield 41%). MS (m/e): 479.8 (M+H+, 100%).

WORKUP

后处理

  1. customThe crude material was purified by chromatography (SiO2, ethyl acetate/heptane)