HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(5-Trifluoromethyl-thiazol-2-yl)-piperazine hydrochloride → HCID 21100232, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(5-Trifluoromethyl-thiazol-2-yl)-piperazine hydrochloride | HCID 21100200 | — |
| Reactant | HCID 21100231 | HCID 21100231 | — |
| Product | HCID 21100232 | HCID 21100232 | 41% |
Reaction Steps
Prepared in analogy to example 1 (b) from 2-ethylsulfanyl-5-methanesulfonyl-benzoic acid (Example A23) and 1-(5-trifluoromethyl-thiazol-2-yl)-piperazine hydrochloride (Example 58(c)). The crude material was purified by chromatography (SiO2, ethyl acetate/heptane) to yield the title compound as a white foam (yield 41%). MS (m/e): 479.8 (M+H+, 100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07220744B2 |
| Source dataset | uspto-grants-2007_05 |
| ORD ID | ord-3c0a193d4d024cc69486bddb84b925c6 |
| Source note | uspto-grants-2007_05 |