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HRID1352410

反应详情

EQUATION

反应方程式

HRID 1352410 的结构方程式

REACTANTS

反应物

2
结构：N#Cc1cnc(N2CCNCC2)s1
HCID21100257

未命名化合物

结构：CC(C)Oc1ccc(C#N)cc1C(=O)O
HCID21100297

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)Oc1ccc(C#N)cc1C(=O)N1CCN(c2ncc(C#N)s2)CC1
HCID21100216

未命名化合物

收率 70%

PROCEDURE

实验过程

Prepared in analogy to example 1 (b) from 5-cyano-2-isopropoxy-benzoic acid (Example A28) and 2-piperazin-1-yl-thiazole-5-carbonitrile (Example 6(a)). The crude material was purified by chromatography (SiO2, ethyl acetate/heptane) to yield the title compound as a white solid (yield 70%). MS (m/e): 382.3 (M+H+, 100%).

WORKUP

后处理

  1. customThe crude material was purified by chromatography (SiO2, ethyl acetate/heptane)