Hydrochloric Acid → HCID 10294326, compound

HRID 1352691Notes

Reaction equation

HRID 1352691 reaction equation
[CH2:1]1[NH:6][CH2:5][CH2:4][N:3]2[CH2:7][C@H:8]([CH2:11][N:12]3[C:16]4[CH:17]=[CH:18][CH:19]=[CH:20][C:15]=4[O:14][C:13]3=[O:21])[CH2:9][CH2:10][C@@H:2]12.Cl[C:23]1[CH:28]=[CH:27][C:26]([Cl:29])=[CH:25][N:24]=1.Cl>>[Cl:29][C:26]1[CH:27]=[CH:28][C:23]([N:6]2[CH2:5][CH2:4][N:3]3[CH2:7][C@H:8]([CH2:11][N:12]4[C:16]5[CH:17]=[CH:18][CH:19]=[CH:20][C:15]=5[O:14][C:13]4=[O:21])[CH2:9][CH2:10][C@H:2]3[CH2:1]2)=[N:24][CH:25]=1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 276852,5-DichloropyridineHCID 54267040HCID 54267040, compound

Product 1

HCID 10294326HCID 10294326, compound

Procedure

The title compound was synthesized according to Preparation 11 from 3-[(7R,9aS)-2,3,4,6,7,8,9,9a-octahydro-1H-pyrido[1,2-a]-pyrazin-7-ylmethyl]-3H-benzoxazol-2-one (Preparation 12) and 2,5-dichloropyridine. mp (.HCl) 247–248° C. HRMS calcd for C21H23ClN4O2: 398.1510, found: 398.1484.

Sources & evidence

ORD record
ord-a6cdd5bd7579432d82d6b5d36f61d882
Source dataset
uspto-grants-2007_05
Patent number
US07220753B2

Reaction notes

Loading…