Lithium Hydroxide → HCID 18322853, compound

Participants

Reaction Steps

LiOH x H2O (775 mg) was added to a solution of ethyl 3-{2-[(3-(guanidino)benzoyl)amino]acetamido}-3-phenyl-propanoate from II.1-E (2.0 g) in 100 ml of water and the mixture was stirred at room temperature for 1 h. It was then neutralized with trifluoroacetic acid and concentrated. After purification by HPLC, a white solid was obtained (yield: 1.4 g).

Provenance & Evidence