反应详情

8.2 g of the compound obtained in Step 2 was added to a mixture of 320 ml of acetic acid and 120 ml of water, and 400 ml of 10% aqueous copper sulfate was added thereto. The resulting mixture was refluxed for 24 hours while removing water using a Dean-Stark trap, and the residue was dried to obtain 5.8 g (yield: 87.1%) of the title compound.

1. additionwas added
2. temperatureThe resulting mixture was refluxed for 24 hours
3. customwhile removing water using a Dean-Stark trap
4. customthe residue was dried