HRID1353267

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CC(Cc1ccc(OCC(=O)NCCc2ccc(Oc3ccccc3)cc2)cc1)(Oc1ccccc1)C(=O)O

HCID23132752

未命名化合物

结构：CCOC(=O)C(C)(Cc1ccc(O)cc1)Oc1ccc(OC(F)(F)F)cc1

HCID69320543

未命名化合物

PRODUCTS

生成物

结构：CC(Cc1ccc(OCC(=O)NCCc2ccc(Oc3ccccc3)cc2)cc1)(Oc1ccc(OC(F)(F)F)cc1)C(=O)O

HCID23132758

未命名化合物

PROCEDURE

实验过程

The title compound was prepared using same method for 2-Methyl-2-phenoxy-3-(4-{[2-(4-phenoxy-phenyl)-ethylcarbamoyl]-methoxy}-phenyl)-propionic acid from 3-(4-Hydroxy-phenyl)-2-methyl-2-(4-trifluoromethoxy-phenoxy)-propionic acid ethyl ester.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-3813f113b23d442d89c080d17248336f
来源数据集: uspto-grants-2007_05
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07220880B2
来源说明: uspto-grants-2007_05

反应 SMILES

[CH3:1][C:2]([O:33][C:34]1[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=1)([CH2:6][C:7]1[CH:12]=[CH:11][C:10]([O:13][CH2:14][C:15](=[O:32])[NH:16][CH2:17][CH2:18][C:19]2[CH:24]=[CH:23][C:22]([O:25][C:26]3[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=3)=[CH:21][CH:20]=2)=[CH:9][CH:8]=1)[C:3]([OH:5])=[O:4].C(OC(=O)C(C)(OC1C=CC([O:60][C:61]([F:64])([F:63])[F:62])=CC=1)CC1C=CC(O)=CC=1)C>>[CH3:1][C:2]([O:33][C:34]1[CH:35]=[CH:36][C:37]([O:60][C:61]([F:64])([F:63])[F:62])=[CH:38][CH:39]=1)([CH2:6][C:7]1[CH:8]=[CH:9][C:10]([O:13][CH2:14][C:15](=[O:32])[NH:16][CH2:17][CH2:18][C:19]2[CH:24]=[CH:23][C:22]([O:25][C:26]3[CH:27]=[CH:28][CH:29]=[CH:30][CH:31]=3)=[CH:21][CH:20]=2)=[CH:11][CH:12]=1)[C:3]([OH:5])=[O:4]