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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1353267Generated: November 1, 2026

2-Methyl-2-phenoxy-3-(4-{[2-(4-phenoxy-phenyl)-ethylcarbamoyl]-methoxy}-phenyl)-propionic acid → 2-Methyl-3-(4-{[2-(4-phenoxy-phenyl)-ethylcarbamoyl]-methoxy}-phenyl)-2-(4-trifluoromethoxy-phenoxy)-propionic acid

https://huagongshe.com/reaction/1353267

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methyl-2-phenoxy-3-(4-{[2-(4-phenoxy-phenyl)-ethylcarbamoyl]-methoxy}-phenyl)-propionic acidHCID 23132752—
Reactant2-(4-Trifluoromethoxyphenoxy)-3-(4-hydroxyphenyl)-2-methyl-propionic acid ethyl esterHCID 69320543—
Product2-Methyl-3-(4-{[2-(4-phenoxy-phenyl)-ethylcarbamoyl]-methoxy}-phenyl)-2-(4-trifluoromethoxy-phenoxy)-propionic acidHCID 23132758—

Reaction Steps

The title compound was prepared using same method for 2-Methyl-2-phenoxy-3-(4-{[2-(4-phenoxy-phenyl)-ethylcarbamoyl]-methoxy}-phenyl)-propionic acid from 3-(4-Hydroxy-phenyl)-2-methyl-2-(4-trifluoromethoxy-phenoxy)-propionic acid ethyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07220880B2
Source datasetuspto-grants-2007_05
ORD IDord-3813f113b23d442d89c080d17248336f
Source noteuspto-grants-2007_05