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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1353289Generated: November 1, 2026

1-(4-Fluorobenzyl)piperazine → HCID 58646609, compound

https://huagongshe.com/reaction/1353289

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(4-Fluorobenzyl)piperazineHCID 796563—
Reactant(2S,1R)-2-ethoxy-3-(4-{1-[2-(4-phenoxy-phenyl)-ethylcarbamoyl]-ethoxy}-phenyl)propionic acidHCID 9847886—
ProductHCID 58646609HCID 58646609—

Reaction Steps

The title compound was prepared from (2S)-3-(4-carboxymethoxy-phenyl)-2-methoxy-ropionic acid ethyl ester (PREPARATION 3, step 2) and 1-(4-fluoro-benzyl)-piperazine via the same procedure used for the preparation of (2S,1R)-2-ethoxy-3-(4-{1-[2-(4-phenoxy-phenyl)-ethylcarbamoyl]-ethoxy}-phenyl)-propionic acid (Example 1, step 3) to produce a colorless oil. MS (ES) for C23H27FN2O5 [M+H]+: 431.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07220880B2
Source datasetuspto-grants-2007_05
ORD IDord-3485828556d5499db7b1abee0d9c4354
Source noteuspto-grants-2007_05