HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piperazine → 7-Chloro-4-(piperazin-1-yl)quinoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piperazine | HCID 4837 | — |
| Reactant | 4,7-Dichloroquinoline | HCID 6866 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 7-Chloro-4-(piperazin-1-yl)quinoline | HCID 738389 | 65.4% |
Reaction Steps
4,7-Dichloroquinoline (9.9 g, 50 mmol) and piperazine (43.1 g, 500 mmol) in EtOH (200 mL) are reacted according to method B yielding 8.10 g of the product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07220856B2 |
| Source dataset | uspto-grants-2007_05 |
| ORD ID | ord-ed1fa5c644344a5cafb1740fede11b3f |
| Source note | uspto-grants-2007_05 |