HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 21101706, compound → HCID 21101785, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 21101706 | HCID 21101706 | — |
| Reactant | Trifluoroacetic acid methylene chloride | HCID 21863450 | — |
| Solvent | 4-Fluorophenyl isocyanate | HCID 70955 | — |
| Product | HCID 21101785 | HCID 21101785 | — |
Reaction Steps
4-[4-(tert-Butoxycarbonyl)piperazin-1-yl]-7-chloro-2-quinolone (100 mg) is deprotected with TFA-CH2Cl2 1:1 (0.5 mL) and transformed to the title product with 4-fluorophenyl isocyanate (50 μL) according to method C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07220856B2 |
| Source dataset | uspto-grants-2007_05 |
| ORD ID | ord-d437eeb49f114741a527fb1c58b8534c |
| Source note | uspto-grants-2007_05 |