HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 21101588, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 21101701 | HCID 21101701 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 21101588 | HCID 21101588 | — |
Reaction Steps
4-[4-(tert-Butoxycarbonyl)piperazin-1-yl]-2-(n-butylamino)-7-chloroquinoline (47 mg, 0.11 mmol) is deprotected with TFA in CH2Cl2 and transformed into the title product according to method C using 4-fluorophenyl isocyanate (18 μL, 0.16 mmol) and triethylamine (110 μL, 0.79 mmol) to give a colorless solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07220856B2 |
| Source dataset | uspto-grants-2007_05 |
| ORD ID | ord-9f4ca205939c41fba8b13c7a85cc7413 |
| Source note | uspto-grants-2007_05 |