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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1353356Generated: November 1, 2026

4-Fluorophenyl isocyanate → HCID 21101749, compound

https://huagongshe.com/reaction/1353356

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluorophenyl isocyanateHCID 70955—
ReactantHCID 21101960HCID 21101960—
SolventDichloromethane methanolHCID 21226129—
ProductHCID 21101749HCID 21101749—

Reaction Steps

7-Chloro-4-(3,5-dimethylpiperazin-1-yl)quinoline (100 mg, 0.36 mmol) and 4-fluorophenyl isocyanate (70 mg, 0.51 mmol) are reacted according to method C yielding the title product as colorless solid after column chromatography with CH2Cl2-MeOH.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07220856B2
Source datasetuspto-grants-2007_05
ORD IDord-11608132e6a84c5db0283b369d94c6ba
Source noteuspto-grants-2007_05