HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diisopropylethylamine → HCID 21101688, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | 4-Acetylphenyl isocyanate | HCID 99452 | — |
| Reactant | 7-Chloro-4-(piperazin-1-yl)quinoline | HCID 738389 | — |
| Reactant | HCID 2809985 | HCID 2809985 | — |
| Solvent | Dichloromethane methanol | HCID 21226129 | — |
| Product | HCID 21101688 | HCID 21101688 | — |
Reaction Steps
As described for 7-chloro-4-[4-(4-trifluoromethylphenylaminocarbonyl)piperazin-1-yl]quinoline, 7-chloro-4-(piperazin-1-yl)quinoline (250 mg, 1.01 mmol), diisopropyl(ethyl)amine (261 mg, 2.02 mmol), and 4-acetylphenyl isocyanate (195 mg, 1.21 mmol) are reacted to give the title product after flash chromatography with CH2Cl2-MeOH.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07220856B2 |
| Source dataset | uspto-grants-2007_05 |
| ORD ID | ord-1f135af852c84e58a1b5e7c19dff80e0 |
| Source note | uspto-grants-2007_05 |