HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diisopropylethylamine → HCID 21101765, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | 7-Chloro-4-(piperazin-1-yl)quinoline | HCID 738389 | — |
| Reactant | HCID 2809985 | HCID 2809985 | — |
| Reactant | 4-(6-Methyl-2-benzothiazolyl)phenyl isocyanate | HCID 4616898 | — |
| Solvent | Dichloromethane methanol | HCID 21226129 | — |
| Product | HCID 21101765 | HCID 21101765 | — |
Reaction Steps
As described for 7-chloro-4-[4-(4-trifluoromethylphenylaminocarbonyl)piperazin-1-yl]quinoline, 7-chloro-4-(piperazin-1-yl)quinoline (120 mg, 0.49 mmol), diisopropyl(ethyl)amine (127 mg, 0.98 mmol), and 4-(6-methyl-2-benzothiazolyl)phenyl isocyanate (100 mg, 0.38 mmol) are reacted to give the title product after flash chromatography with CH2Cl2-MeOH.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07220856B2 |
| Source dataset | uspto-grants-2007_05 |
| ORD ID | ord-29de5053121641bdad5cf0739790a92b |
| Source note | uspto-grants-2007_05 |