HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tert-Butylamine → HCID 178449183, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tert-Butylamine | HCID 6385 | — |
| Reactant | HCID 87869961 | HCID 87869961 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | HCID 178449183 | HCID 178449183 | — |
Reaction Steps
7-Chloro-4-[4-(cyanimino(phenoxy)methyl)piperazin-1-yl]quinoline (53 mg, 0.14 mmol) and tert-butylamine (2.0 mL, 19 mmol) are heated in pyridine (10 mL) for 6 h at reflux. The solvent is removed, and the residue purified by column chromatography with CH2Cl2-MeOH giving the title product as a colorless solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07220856B2 |
| Source dataset | uspto-grants-2007_05 |
| ORD ID | ord-be30d6c861fe41ea91543657f16b8e92 |
| Source note | uspto-grants-2007_05 |