HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methylcyclohexylamine → HCID 21101758, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methylcyclohexylamine | HCID 23432 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | 4-Nitrophenyl chloroformate | HCID 82129 | — |
| Reactant | 7-Chloro-4-(piperazin-1-yl)quinoline | HCID 738389 | — |
| Solvent | Dichloromethane methanol | HCID 21226129 | — |
| Product | HCID 21101758 | HCID 21101758 | — |
Reaction Steps
As described for example 78, 2-methylcyclohexylamine (170 mg, 1.5 mmol), 4-nitrophenyl chloroformate (302 mg, 1.5 mmol), diisopropyl(ethyl)amine (469 mg, 3.7 mmol), and 7-chloro-4-(piperazin-1-yl)quinoline (248 mg, 1.0 mmol) are reacted affording the title product after flash chromatography with CH2Cl2-MeOH.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07220856B2 |
| Source dataset | uspto-grants-2007_05 |
| ORD ID | ord-ca97c0a2a400429c9eb9fc2e4001a5ef |
| Source note | uspto-grants-2007_05 |