Benzene, 1-isocyanato-2-methoxy- → HCID 21101672, compound

Participants

Reaction Steps

As described for example 159, 7-chloro-4-(1-piperazinyl)-2-quinolinamine, 1-isocyanato-2-methoxy-benzene, and diisopropylethyl amine, are reacted to give the title product. LC-MS: 411 (M++1). 1H NMR (CDCl3) δ 3.15–3.25 (m, 4H), 3.7–3.85 (m, 4H), 3.9 (s, 3H), 4.6–4.8 (s, 2H), 6.2 (s, 1H), 6.86–6.9 (m, 1H), 6.94–7.02 (m, 2H), 7.16–7.21 (m, 2H), 7.62–7.65 (d, 1H), 7.74–7.78 (d, 1H), 8.14–8.19 (m, 1H).

Provenance & Evidence