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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1353444Generated: November 2, 2026

Ethyl isocyanate → HCID 21101681, compound

https://huagongshe.com/reaction/1353444

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl isocyanateHCID 8022—
ReactantDiisopropylethylamineHCID 81531—
Reactant7-Chloro-4-(1-piperazinyl)-2-quinolinamineHCID 21101748—
ProductHCID 21101681HCID 21101681—

Reaction Steps

As described for example 159, 7-chloro-4-(1-piperazinyl)-2-quinolinamine, ethylisocyanate, and diisopropylethyl amine, are reacted to give the product. LC-MS: 333 (M++1). 1H NMR (DMSO-d6): 61.0 (t, 3H), 2.8–3.0 (m, 4H), 3.0–3.14 (q, 2H), 3.45–3.6 (m, 4H), 6.25 (s, 1H), 6.4–6.55 (s, 2H), 6.55–6.65 (m, 1H), 7.1–7.2 (m, 1H), 7.35–7.4 (m, 1H), 7.7–7.8 (d, 1H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07220856B2
Source datasetuspto-grants-2007_05
ORD IDord-f0cd5d5074984467824853b37125e7a2
Source noteuspto-grants-2007_05