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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1353446Generated: October 31, 2026

Diisopropylethylamine → HCID 21101665, compound

https://huagongshe.com/reaction/1353446

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiisopropylethylamineHCID 81531—
Reactant7-Chloro-4-(1-piperazinyl)-2-quinolinamineHCID 21101748—
ReactantHCID 21101827HCID 21101827—
ProductHCID 21101665HCID 21101665—

Reaction Steps

As described example 159, 7-chloro-4-(1-piperazinyl)-2-quinolinamine, 3-isocyanato-2(1H)-pyridinone, and diisopropylethyl amine, are reacted to give the title product as a white solid. LC-MS: 399 (M++1). 1H NMR (DMSO-d6) δ 7.95 (m, 2H), 7.76 (d, 1H), 7.40 (s, 1H), 7.12 (m, 1H), 7.0 (d, 1H), 6.45 (m, 2H), 6.25 (s, 1H), 6.22 (m, 1H), 3.75 (m, 4H), 3.10 (m, 4H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07220856B2
Source datasetuspto-grants-2007_05
ORD IDord-0a6cabf912b242dea1a30f729af9fb4d
Source noteuspto-grants-2007_05