Diisopropylethylamine → HCID 21101667, compound

Participants

Reaction Steps

As described for example 159, 7-chloro-4-(1-piperazinyl)-2-quinolinamine, 1,1,1-trifluoro-2-isothiocyanato-ethane, and diisopropylethyl amine, are reacted to give the product. LC-MS: 466 (M++1). 1H NMR (DMSO-TFA-d6) δ 1.0–1.3 (m, 1H), 3.0–3.14 (d, 1H), 3.18–3.38 (m, 6), 3.38–3.7 (m, 7H), 4.6–4.8 (m, 1H), 6.2–6.4 (s, 1H), 6.7–7.0 (m, 1H), 7.28–7.44 (m, 1H), 7.6–7.7 (s, 1H), 7.8–8.0 (m, 1H), 8.1–8.2 (m, 1H).

Provenance & Evidence