HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluorophenyl isothiocyanate → HCID 21101677, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluorophenyl isothiocyanate | HCID 15241 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | 7-Chloro-4-(1-piperazinyl)-2-quinolinamine | HCID 21101748 | — |
| Product | HCID 21101677 | HCID 21101677 | — |
Reaction Steps
As described for example 159, 7-chloro-4-(1-piperazinyl)-2-quinolinamine, 4-fluorophenyl isothiocyanate, and diisopropylethyl amine, are reacted to give the product as a white solid. LC-MS: 416 (M++1). 1H NMR (DMSO-d6) δ 3.10 (br.s, 4H), 4.15 (br.s, 4H), 6.20 (s, 1H), 6.45 (br.s, 2H), 7.10 (m, 3H), 7.30 (m, 2H), 7.40 (s, 1H), 7.80 (d, 1H), 9.42 (br.s, 1H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07220856B2 |
| Source dataset | uspto-grants-2007_05 |
| ORD ID | ord-c0d86b0c2796421fb052011faeeb01a0 |
| Source note | uspto-grants-2007_05 |