Diisopropylethylamine → HCID 58864150, compound

Participants

Reaction Steps

As described for example 78, 7-chloro-4-aminoqunoline, p-nitrophenyl chloroformate, diisopropylethyl amine, and 7-chloro-4-(1-piperazinyl)-2-quinolinamine are reacted to afford the product. LC-MS: 427 (M++1). 1H NMR (DMSO-d6) δ 3.0–3.2 (m, 4H), 3.6–3.9 (m, 4H), 6.2–6.3 (s, 1H), 6.4–6.6 (s, H), 7.05–7.2 (m, 1H), 7.35–7.4 (m, 1H), 7.4–7.5 (d, 2H), 7.7–7.8 (d, 1H), 8.2–8.35 (d, 2H).

Provenance & Evidence