HRID1353561

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID24654

Hydrazine hydrate (1:1)

H6N2O

结构：CN(C)C=C1CN(C(=O)OC(C)(C)C)CC(C)(C)C1=O

HCID68707465

未命名化合物

PRODUCTS

生成物

HCID37818370

tert-Butyl 7,7-dimethyl-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridine-5-carboxylate

C13H21N3O2

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID887

Methanol

CH4O

PROCEDURE

实验过程

To a solution of 5-dimethylaminomethylene-3,3-dimethyl-4-oxo-piperidine-1-carboxylic acid tert-butyl ester (6.35 g, 22 mmol) in methanol (15 mL) was added hydrazine hydrate (1.2 mL, 1.1 equiv). The solution was stirred at room temperature overnight and concentrated to give 5.3 g (94%) which was used without purification. Mass spec.: 252.19 (MH)+.

WORKUP

后处理

concentrationconcentrated
customto give 5.3 g (94%) which
customwas used without purification