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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1353709Generated: October 30, 2026

HCID 22480224, compound → HCID 22480316, compound

https://huagongshe.com/reaction/1353709

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 22480224HCID 22480224—
SolventMethanolHCID 887—
ProductHCID 22480316HCID 2248031647%

Reaction Steps

The title compound was prepared as described in Example 141 A, using 5-[(1 E)-2-pyridylvinyl]-3-(4-fluorophenyl)-1H-indazole (0.125 g, 0.4 mmol) in methanol and it was then purified by HPLC (0.060 g, 47% yield): 1H NMR (DMSO-d6) δ 13.14 (br s, 1H), 8.52 (d, 1H), 7.95 (m, 2H), 7.79 (s, 1H), 7.69 (ddd, 1H), 7.42 (dd, 1H), 7.22–7.35 (m, 5H), 3.12 (m, 4H); ES-MS (m/z) 318 [M+1]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07220771B2
Source datasetuspto-grants-2007_05
ORD IDord-128621ef9ec44b7791dc758dcdd984b1
Source noteuspto-grants-2007_05