Propargylamine → HCID 21103274, compound

HRID 1354080Notes

Reaction equation

HRID 1354080 reaction equation
C([O:3][C:4]([CH2:6][N:7]([S:15]([C:18]1[CH:23]=[CH:22][C:21]([O:24][CH3:25])=[CH:20][CH:19]=1)(=[O:17])=[O:16])[CH:8]([CH2:13]O)[C:9]([O:11][CH3:12])=[O:10])=O)C.[CH2:26]([NH2:29])[C:27]#[CH:28]>>[CH3:25][O:24][C:21]1[CH:20]=[CH:19][C:18]([S:15]([N:7]2[CH2:6][C:4](=[O:3])[N:29]([CH2:26][C:27]#[CH:28])[CH2:13][CH:8]2[C:9]([O:11][CH3:12])=[O:10])(=[O:16])=[O:17])=[CH:23][CH:22]=1

Participants

3

Reactant 2

HCID 239041PropargylamineHCID 11234214HCID 11234214, compound

Product 1

HCID 21103274HCID 21103274, compound

Procedure

A title compound was prepared by the same method as in Example 4, except that it was prepared from the compound of Example 3 and propargylamine, and recrystallized with CH3Cl/hexane to obtain a white solid (yield 90%).

Workup

  1. customrecrystallized with CH3Cl/hexane

Sources & evidence

ORD record
ord-81150090f38247069b90421d0268793a
Source dataset
uspto-grants-2007_05
Patent number
US07223751B2

Reaction notes

Loading…