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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1354179Generated: November 4, 2026

Acetoxyacetyl chloride → HCID 21104418, compound

https://huagongshe.com/reaction/1354179

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetoxyacetyl chlorideHCID 26297—
ReactantHCID 9845828HCID 9845828—
Catalyst4-(Dimethylamino)pyridineHCID 14284—
SolventDiisopropylethylamineHCID 81531—
ProductHCID 21104418HCID 21104418—

Reaction Steps

By using 4-[2-(3-fluoro-phenyl)-6-trifluoromethyl-pyrazolo[1,5-a]pyridin-3-yl]benzenesulfonamide (0.15 g 0.35 mmol), diisopropylethylamine (Aldrich) (150 μl ), 4-dimethylaminopyridine (0.04 g 0.32 mmol) and acetoxyacetyl chloride (Aldrich) (0.109 g 0.8 mmol), the title compound was obtained in the manner of Example 19 as a white solid (0.14 g 75%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07223772B1
Source datasetuspto-grants-2007_05
ORD IDord-3eafc36aa09441ad833a0c60e782a578
Source noteuspto-grants-2007_05