HCID 21104615, compound → HCID 21104620, compound

Participants

Reaction Steps

A solution of 4-[2-(1,4-dioxa-spiro[4.5]dec-8-yl)-ethyl]-6-methoxy-quinoline (0.77 g, 2.35 mmol) in AcOH/THF/H2O (3/2/2, 10 ml) was stirred at 60° C. for 10 hours. The reaction mixture was concentrated to dryness by rotary evaporation. The residue was diluted with EtOAc (100 ml), washed with NaHCO3 (100 ml), dried over MgSO4, filtered and concentrated to dryness by rotary evaporation.

Provenance & Evidence