HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 178487893, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | Tert-butyl [4-(6-methoxy-quinolin-4-yloxymethyl)-cyclohexyl]carbamate | HCID 58603138 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 178487893 | HCID 178487893 | — |
Reaction Steps
A solution of tert-butyl [4-(6-methoxy-quinolin-4-yloxymethyl)-cyclohexyl]carbamate (438 mg, 1.13 mmol) and TFA (1.5 ml) in dichloromethane (4 ml) was stirred at room temperature for 2 hours. The reaction mixture was poured onto ice/ammonium hydroxide and extracted with dichloromethane. The organic extracts were dried over Na2SO4 and concentrated.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07223776B2 |
| Source dataset | uspto-grants-2007_05 |
| ORD ID | ord-a88c777995d248cb91e4beda7d532182 |
| Source note | uspto-grants-2007_05 |