Methanol → HCID 21104871, compound

HRID 1354276Notes

Reaction equation

HRID 1354276 reaction equation
C(ON[C:10]([C@H:12]1[C@H:17]([OH:18])[C@H:16]([OH:19])[C@@H:15]([OH:20])[CH2:14][N:13]1[S:21]([C:24]1[CH:29]=[CH:28][C:27]([O:30][CH3:31])=[CH:26][CH:25]=1)(=[O:23])=[O:22])=[O:11])C1C=CC=CC=1.C[OH:33]>[Pd]>[OH:18][C@@H:17]1[C@H:16]([OH:19])[C@@H:15]([OH:20])[CH2:14][N:13]([S:21]([C:24]2[CH:29]=[CH:28][C:27]([O:30][CH3:31])=[CH:26][CH:25]=2)(=[O:23])=[O:22])[C@H:12]1[C:10]([OH:33])=[O:11]

Participants

4

Reactant 2

HCID 887MethanolHCID 58866161HCID 58866161, compound

Product 1

HCID 21104871HCID 21104871, compound

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

The above compound (6) (316 mg) was dissolved in methanol (25 mL) and 10% Pd—C (40 mg) was added, and then the mixture was stirred under a hydrogen atmosphere at room temperature for 2 hours. The catalyst was removed by filtration and the filtrate was concentrated under reduced pressure to obtain the titled compound (242 mg) as a colorless powder.

Workup

  1. customThe catalyst was removed by filtration
  2. concentrationthe filtrate was concentrated under reduced pressure

Sources & evidence

ORD record
ord-86afaaa1fa474c74bd5160efd5fe7704
Source dataset
uspto-grants-2007_05
Patent number
US07223779B2

Reaction notes

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