反应详情

1-Amino-1H-pyrrole-2-carbonitrile (2.52 g, 23.5 mmole) was suspended in 75 ml water, treated with potassium hydroxide (32 g, 0.57 mole), 30% hydrogen peroxide (2 ml) and stirred overnight at room temperature. Cooled reaction mixture to 0° C. for 30 min and isolated product by filtration, washed with cold water and dried under vacuum to give 2.55 g product (yield: 87%)

1. temperatureCooled
2. customreaction mixture to 0° C. for 30 min
3. customisolated product
4. filtrationby filtration
5. washwashed with cold water
6. customdried under vacuum